A QUANTITATIVE COLOR REACTION FOR CORTISONE AND RELATED 17,21-DIHYDROXY-20-KETOSTEROIDS
نویسندگان
چکیده
منابع مشابه
A Quantitative Color Reaction for Cortisone and Related 17,21-dihydroxy-20-ketosteroids By
The numerous combinations of functional groups occurring in the steroid hormones render difficult the development of a specific test for individual compounds. However, reactions which reveal certain groupings are available and may be applied singly or in combination to elucidate the characteristics of pure steroids or of compounds in a mixture. The ketol side chain, located at carbon atom 17 in...
متن کاملThe determination of 17,21-dihydroxy-20-ketosteroids in urine and plasma.
In 1950 (l), the authors described a color reaction between 17,21-dihydroxy-20-ketosteroids and phenylhydrazine and showed that, after addition of 1 r or more of cortisone per ml. of urine or plasma, about 88 per cent could be detected in chloroform extracts. Nelson and Samuels (2) improved the procedure, primarily by employing chromatographic separation and micro cuvettes, so that they were ab...
متن کاملAbsorption and excretion of 17, 21-dihydroxy-20-ketosteroids in dogs.
tions of hydrocortisone and cortisone to man have established the plasma half-life of hydrocortisone to be 2 hours and that of cortisone 1 hour (1, 2). From isotopic determinations in urine, the half-life of hydrocortisone in the body has been found to be 6 hours and that of cortisone 3.6 hours (3, 4). Thus, cortisone is not only cleared from the plasma more rapidly than hydrocortisone but it i...
متن کاملA method for the quantitative determination in urinary extracts of C21 17:20-dihydroxy-20-methylsteroids.
Hyperactivity of the adrenal cortex in human subjects due to malignant neoplasm, hyperplasia or stimulation by adrenocorticotropic hormone (ACTH) has frequently been observed to be associated with the urinary excretion of considerable amounts of various C21 20-methylsteroids (see Table 1). possibility and because of the widespread therapeutic use of 17-hydroxy-1 1-dehydrocorticosterone (cortiso...
متن کاملpassivity in waiting for godot and endgame: a psychoanalytic reading
this study intends to investigate samuel beckett’s waiting for godot and endgame under the lacanian psychoanalysis. it begins by explaining the most important concepts of lacanian psychoanalysis. the beckettian characters are studied regarding their state of unconscious, and not the state of consciousness as is common in most beckett studies. according to lacan, language plays the sole role in ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1950
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)56408-5